I agree that MD Relics is great in the current meta. And they open up your sideboard for combo hate beautifully.
A friend of mine won one of the GP trials with Mono-Red gobs. 3 MD relics.
The more I think on it, I like the idea of Chalice plus Thorn for the combo MU. First turn chalice at 0 buys you some time by slowing their acceleration. And the great thing about thorn is that it increases the cost of their bounce spells. Probably buying you a turn or two. Multiple thorns are even better. Usually when you cast multiple hate, they can get echoed back to your hand. But multiple thorns make echoing truth that much harder to play.
i haven't tested thorn yet though, I'm just speculating.

