Even decks with overpowered draw engines like Ad Nauseam run only 6-8 maindeck disruption spells. In testing, I've found that Solidarity can reasonably handle 8 disruption elements, but more than that is starting to push the limits.
Given the fact that four of my disruption slots will go to FoW, it's a question of what is best put in the other four slots. Remand is a strong contender, as it's great against every deck on the play. On the draw, however, it's actually quite slow. That's alright against control decks and combo decks that are having to pick their way through your other disruption or sculpt their hand. But it's not exactly great, and it's absolutely dire against aggro. With a good hand, Zoo does not actually need to cast anything after turn two in order to win on turn four. Neither does Goblins.
For this reason, I am currently splitting my final four disruption slots between Clique and Remand. Against aggro, Clique is simply removal, while it's disruption and a clock against combo and control. In truth, Clique is strongest post board, when all the creature removal is gone, but I currently lack the space in my sideboard to take Clique out of the maindeck.
I've been testing Tangle, and I really like it against Zoo. With 8 fetches, I've only once failed to find my Tropical by turn three, and you can often chain one Tangle into another. It's not perfect, as it only buys you 1.5 turns rather than 2, but it helps a great deal. Currently, I'm boarding in 3 Tangle and taking out 1 Brain Freeze (so none in the main deck) and 2 Remand (meaning none in the maindeck). This leaves me Clique as removal for hate bears, which takes some of the pressure off my Wishes.
Currently, my sideboard looks like this:
1 BSZ
1 Brain Freeze
1 Meditate
1 Turnabout
1 Rebuild
1 Echoing Truth
1 Hunting Pack
2 Krosan Grip
3 Flusterstorm
1 Ravenous Trap
2 Surgical Extraction
The way I see it, I get a wishboard and then three matches get a sideboard. Currently, I'm boarding for Reanimator/Dredge, Countertop and Combo/Control. I need to make room for my aggro board, and the cards dedicated to Countertop are the narrowest, so I'll probably drop two Grip and something else for three Tangle.
I'm toying with removing Rebuild, but I sometimes side it in where I expect Cannonists (I can still wish for Echoing Truth). I also rarely wish for Turnabout because it is so mana intensive, so that could possibly go.
I'd love to squeeze Snap in there, because I find that bouncing a hatebear before going off (such as Meddling Mage or Cannonist) is very mana intensive, whereas Snap makes the whole process fairly painless. I still feel I ought to have something for Counterbalance, though, even if it's just a single Wipeaway.

