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The reason these solutions seem a fuckload more suboptimal than Gaunlet is that they all ask What can I do to make up for all the dead cards E. Plague gives me? whereas Gauntlet asks What can I do to make that E. Plague not matter?
Also, unlike Naturalize, it can be proactive. Even without an E. Plague to counter, it gives you the option of dealing an extra 4-5 damage the turn you drop it and just winning. Also unlike Naturalize, it can partially or fully counter a Pyroclasm, Hideous Laughter, Hail Storm, Infest, or Plague Spitter.
Also unlike Naturalize, a playset costs about 350$
The reason that I suggested Patron is that it is useful in multiple matchups, not just the Engineered Plague one. I'd much rather have Patron of the Akki against random bad aggro decks (or even random very good ones) than I would Gauntlet of Might. Patron's on the average cheaper (with Goblin Offering, it's going to cost you anywhere from 3 to 5 mana at instant speed), it provides a giant bonus to your creatures in play (those that live long enough), and comes attached to a 5/5 non-Plagueable body.