I respectfully disagree.
Lands plays around Innocent Blood easily, and they are most likely already playing around Liliana/Smallpox. Sideboarded Diabolic Edict x1-3 seems much more reasonable against Dark Depths, alongside Pithing Needle x2-3 (for Stage.) EoT Stage/Depths activation, their turn 20 you.
DnT is a creature-heavy deck, making it even worse to play Innocent Blood. They will have up to 2-3 creatures on the board, allowing them to sacrifice their worse dude. Their mana-denial plan is actually pretty strong against us, allowing them to pick their windows for getting multiple creatures on the board. I would almost always want Fatal Push to deal with DnT. Maindeck Ratchet Bomb and sideboarded Engineered Plagues are also incredibly good against them, and Darkblast is incredible. Innocent Blood, in my experience, is actually one of the weakest removals the deck can play.
This is all in my experience of course, but I think Fatal Push, and even more so Collective Brutality, have replaced Innocent Blood. They are just better cards. Most of the rest of the deck is dedicated to doing the traditional Pox plan (smallpox, liliana, pox, targeted discard) so Innocent Blood is the natural place to sub out removal.