Originally Posted by
Mr. Safety
Toxic Deluge is miles better than both, and if you want to get a stacking effect then Engineered Plague is hard to beat. Miracles shrugs off both of those and wins with Jace or 3/3 angels.
The best way to beat miracles is Thoughtseize into Hymn into Liliana. Wasteland is largely ineffective and Smallpox is only good if you've already gotten a jump start with TS/Hymn. Maindeck Ratchet Bomb is good against 4/4 tokens but us too slow against Jace. Sideboarding Needles is important. Blade decks are a little less susceptible to the discard because they can just top deck Batterskull or SFM, and if they play Lingering Souls like Esper blade you're actually in trouble. Lingering Souls is literally one of the best cards against Pox. Again, Ratchet Bomb does a ton of work here. Night OSB is fine as a 1-of, but Dread of Night is too narrow to be considered. Toxic Deluge also deals with Lingering Souls and also deals with Elves, Death and Taxes, Young Pyromancer swarms, and lots of other stuff.
As far as more efficient win-cons go, I have a friend at the LGS that plays Pox regularly and plays 4x Tombstalker. Extras are discarded, and playing them out is easy. It's a fast, evasive clock.