Originally Posted by
Mantis
Opening with Vial vs. Lackey versus an unknown deck.
First and foremost this decision relies on your hand.
A hand like: Vial, Lackey, MWM, Piledriver, Mountain, Port, Wasteland, lends itself much better to a first turn Vial. Whereas a hand with Vial, Lackey, Siege Gang, Gempalm Incinerator, Stingscourger/Warren Weirding, and 3 lands you will obviously lead with Lackey.
Then it depends on whether I am on the play or not. If I am starting leading with Lackey is a lot more appealing since my opponent can't just drop a Goyf and block Lackey all day.
It also depends on how my opponents comes across. I like to believe I can make a decent estamation based on what my opponent looks like in which of the three categories: Storm, CB/Top or other deck he falls into. A player with messy shuffle habits and with a creased piece of paper that he pulls out of his pocket will most likely not be a control player. Against this player I probably want my Vial first as I'm gearing up for the long game. I will put a player that leaves a silent, pseudo autistic appearance on a storm combo pilot, against this player I definately want my Lackey first. This method is nowhere near waterproof obviously, but if you do notice you are good at the guessing game then by all means use it to your advantage I would say.