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Dead in what matchups, exactly? Leyline at least has -some- use against the following:
1. Any deck with a Tarmogoyf.
2. Any deck with Life From The Loam.
3. Survival, or any other deck with Squee, Genesis and Witness.
4. Cephalid Breakfast, Ichorid, or any combo deck that uses Ill-Gotten Gains.
5. Any deck with a Threshold card, be it Mongoose or Monestary.
6. Any deck with any sort of recursion, such as Regrowth in Train Wreck.
7. Any deck with Crucible of Worlds, such as Landstill or Stax.
8. Decks with Rotting Giant or Jotun Grunt, like Deadguy Ale or Red Death.
9. Any deck that has a flashback card in it, including Cabal Therapy or Flash of Insight.
10. Reanimator. Okay, I'm reaching here.
I'll concede the card isn't dead in these matchups. I guess I don't have much of a choice there. But seriously, this is the reason you're running Leyline!?
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While Leyline isn't a bomb against some decks, almost every deck in existence has something graveyard related in it, because they think they can get away with it as long as there's not enough of it to warrant boarding in graveyard hate. Even the ever yard-hate resilient Aluren runs a Witness and sometimes a Deep Analysis, and even Goblins has talked about tossing in Wort, Boggart Auntie and Cabal Therapy, both of which would be hurt by Leyline.
People run Swords to Plowshares because it's useful against over 3/4 of the deck in the format. Leyline's useful against just slightly less.
Those