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I've tested him quite a bit. I love the card. I don't think he is aggressive enough, and in order to run in the main, Affinity variations will need to be adjusted. 8-ball, Erayo-Affinity, and AfFOWnity have the best chances of making a deck can truly abuse him.
E-Canon doesn't belong in the main of Vial Affinity, but if you chose to splash white instead of green, he could be a reasonable anti-combo card. It requires that you bastardize your sideboard to play against combo. You literally have to play 12+ cards against combo to even have a shot.
In my experience, E-Canon is a much stronger card in Vintage than in Legacy. While I love the card, I'm doubtful that this card will be finding a home in Legacy for a while.
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I've tested the card, and outside of the combo match, he is not as powerful as the cards that he would replace. Whatever tempo he provides in the form of timewalks just doesn't make up the lack of damage. In the end, most decks are still just playing about 1 spell a turn anyways. Although it does damage cantrip engines, it isn't worth the loss in damage (which is the strength we have against any blue-based deck with a cantrip engine).
Against non-combo decks, E-Canon just gives them more time to find an answer because you aren't killing them early enough. The Arcane Lab effect, even if mainly one-sided, is just not amazing against any deck that isn't combo.
However, E-Canon is a pimp against combo if you can actually get him into play before you lose.
Vial Affinity has a choice to make about how it will deal with combo in any given metagame. We know the deck simply doesn't belong, regardless of how you build it, in a metagame with any substantial amount of combo, but it is possible for the deck to survive in a metagame with just a couple combo decks, especially if those combo decks are not well-tuned ANT/TES decks with good pilots (that is quite a condition).
If you believe the main is strong enough on its own, with no need for improvement against the majority of your metagame that isn't combo (beyond a few needles), then you can choose to put 12+ combo hate pieces in your side to actually have a shot against some combo decks (of course, not great combo decks and players). I think that is an unlikely metagame for most people though.
The other option is to nearly give up the combo match. This is the price you pay for playing Vial Affinity (or any other aggro deck).
Lastly, E-Canon is white, and that isn't the color I want to play. I'm pretty much convinced that Krosan Grip is mandatory. Splashing for anything other than green is very difficult to accomplish.