Originally Posted by
Mr. Safety
I think Chalice is the same trap as Blood Moon. You're playing to not lose with Moon/Chalice, not playing to win. Yes you get 'free wins' with them occasionally, but I've found that when you use fast mana to play a lock piece you give your opponent at a minimum an extra turn to find an answer (remember, this is with Blood Moon, which requires 3 mana turn 1 to really work out.) I just found that Blood Moon was good, but not great.
Chalice I think is a sideboard card. Maindeck it should probably be focused on being fast and resilient. The sideboard can bring in Chalice to fight the blue crew, although I'm skeptical if it's better than Defense Grid. It really depends on your metagame.