Originally Posted by
OmniStrata
In that case, I'd recommend Trinisphere over Chalice. Chalice doesn't stop Abrupt Decay, however with enough Pox effects, 3sphere can lock them out for quite a few turns. My gripe against chalice is that it completely stops my 1 cmc spells, of which Pox likes to have, however, 3 sphere lets me cast everything, even if it's more expensive mana wise. 3 cmc smallpox with an enemy @ 2 land is 1 sided cheese letting my Nether Spirit's and/or Factories deal free hits. Normally I cheat it into play with D. Ritual. I find that play more powerful than turn 1 Liliana assuming foe didn't counter.