I don't run Sire at all, never missed him really. You definitely don't want 4 MD, 4 Grisel is good enough and you will need those chancellors with so many DRS running around. MDing Elesh or Iona is ok, I got Iona for the mirror. Elesh only really shines against dredge, which is a fringe deck anyway. For elves, either is good enough.
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