Quite a interesting list, Ive toyed with the idea of dropping white and going with just hand disruption as protection but i always figured that between their top and my own IGG id run into trouble.
Giving up green and going with purely wipeaway as splitsecond removal and ditching carpet of flowers and swarm in favor of more basic land and dark confidant+spell pierce

It certainly helps the mana base to include more basics. found myself wishing i played more of those quite often.

three thoughtseize and double ad nauseam does seem like a massive ammount of life loss. Although if you consider using thoughtseize is equal to flipping meditate/doomsday with Adn it doesnt seem that crazy. im not sold on double adn but seeing quite a few lists run two i supose that never has been a issue.