Against D&T it's best to tutor together creatureremoval, and try to diversify this removal.
Playing against D&T is a bit like paper-scissor-rock, they have an answer against all our cards, but we also have an answer to theirs too.

Mother of Runes protecting against a single colored source of damage,
Barbarian Ring killing Mom through colorless damage,
Revoker (or Magus) locking out BRing (or Vortex),
Punishing Fire killing Revoker,
Prelate stopping Loam and Pfire,
and Vortex and Bring killing Prelate.

I feel like we're slightly favored game1, because we have better tutors to shape our paper-scissor-rock game.
But whoever holds scissors against paper (to stay in the metaphor) in the opening hands, has a jumpstart over the opponent.
For me, game 2 and 3 are worse, because our local players pack Surgical extractions besides RIPs in their boards too (because of BR Reanimator I suppose).
Board in Kgrips and possible creatureremoval like Sweepers, Drop ...
I usually side out Karakas/Bog and some Quarters/Ports, as thei're quite resilient to manadenial.
I side out Chasm too, because the local abundance of gravehate prevents it from being effective enough to turn around games.

Against Moon-effects and especially Magus, you can consider running Molten Vortexes in the main.
EDIT: you can kill an active Mom with Pfire by targeting it EOT opp's turn (he taps to protect it), and recur and cast again in your turn.