The Soul Spike was halfass sarcasm, only because a friend of mine and I developed a U/B combo deck around it that's actually got a relatively fast clock for a casual deck (Usually turn 5-6). After posting I realized there's a good chance you'd draw into it with Bob, and that would suck, but I figured it'd be funny to get peoples reactions after I realized how bad it'd be in this deck.

As for Infest, have you ever wanted to go one step further for Mutilate? I've noticed that Infest can't really take down Thresh creatures after about turn 4, and those would seem bad to run into with Negator (Mongoose being a 3/3 and Bear a 4/4). Have you had any issues where you wanted more than -2/-2?

As for Cabal Therapy, it was actually in my Sideboard for a little while, and I didn't mind it that much. It was a good outlet to get rid of Bob if things turned around unfavorably and abruptly, and at times I'd pitch to a creature to take out either a combo piece or a threat I knew was coming that I wouldn't be able to deal with (Mystic Enforcer after thresh, Mongoose, Exalted/Decree/Dragon, basically anything that puts ME on the clock) so the flashback option does end up happening more than people wanted to admit on here so far. Plus, as my arguments earlier stated (probably a few pages back now), it hits creatures, something the deck REALLY wants to do against unfavorable beats.