I can't possibly believe that you can support a deck with 4 Smallpox, 4 Poxes and 2 Deathclouds off of just 22 land!!!
25 is the minimum unless you're playing Flagstones IMO and that's without the death clouds.
I would cut Death Cloud and Engineered Plague for Rancid Earth or Thoughtseize or something.
Otherwise, the build looks cool.
Sample Contamination Deck
Utility
4 Sensei's Divining Top
4 Beseech the Queen
Threats
4 Bitterblossom
3 Nether Spirit
Disruption
4 Thoughtseize
4 Cabal Therapy
4 Duress
4 Hymn to Tourach
4 Contamination
4 Damnation
Mana
4 Dark Ritual
4 Wasteland
3 Sheltered Valley
2 Mishra's Factory
2 Urborg, Tomb of Yawgmoth
3 Polluted Delta
3 Flooded Strand
5 Swamp
IMO, Contamination doest work very well, and is an autoloss against Black decks.
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