In the standard lists, Chalices are entirely proactive cards. While this is good, we run the risk of splash damage when we proactively set them at the wrong numbers.

iostream: The real challenge becomes effective sideboarding. Pick a matchup where you think you will want chalices... and then figure out what to board in and out. It's incredibly difficult to justify taking cards out for chalice of the void in most matchups.

In the Reanimator matchup, Lands was the control, and Reanimator was heavily centered around 1 mana, and board plans did often include boarding one or more chalice. The issue here is that chalice of the void simply isn't as strong of a play as many of our other cards.

Often, sideboarding plans include answers to resolved hate cards or cards that blank hate entirely. In my example board, you care little about hate cards, as your artifacts allow you to play through everything (Crucible is poor against Planar Void and Leyline.) Alternatively, cards like Krosan Grip are boarded in as direct answers.

dahcmai: Although you said you had Chalice, Blue Lands decks now run Tolaria West to tutor up Zuran Orb. A second Zuran Orb may be prudent in some metagames, but I do not believe chalice is the answer you are looking for.